Animal testing articles for and against

Animal testing articles for and against

T he US National Academy of Sciences released a report in envisioning a future in which animals would largely disappear from toxicity testing programs.

The report, drafted by a panel of experts, proposed that toxicity induced animal testing articles for and against drugs, food additives, pesticides, and other chemicals be assessed not by observing overt clinical signs in animals but by monitoring perturbations to biological pathways in cultured human cells.

The long fight against animal testing

Sophisticated bioinformatic technologies could then provide risk predictions that overcome the limitations of animal-based /my-hero-my-brother-essay.html, such as low throughput and the questionable relevance of animal results to human physiology.

Initially, the report was greeted with skepticism, but that skepticism is giving way to guarded excitement. Former Animal testing articles for and against director Elias Zerhouni characterized this effort as the beginning of the end of animal testing. We at The Humane Society of the United States and Humane Society International helped establish a consortium in animal testing articles for and against promote the need for a coordinated international program of research and development akin to the Animal testing articles for and against Genome Project to implement the Animal testing articles for and against vision.

Animal testing articles for and against

We believe that within the next decade or so, we will reach a point where safety testing and risk evaluation of chemicals will be conducted in a fraction of the time, at a fraction of the cost, and with greater predictive relevance for human and environmental safety compared to current, cumbersome animal-based approaches.

The advantages of nonanimal testing methods were illustrated in connection with the recent Gulf of Mexico oil spill. animal testing articles for and against

Experimenting on animals

Animal testing articles for and against after the Deepwater Horizon rig began spewing billions of gallons of animal testing articles for and against into the Gulf, US political leaders asked here EPA to determine the relative safety of eight different commercially available oil dispersants.

Within 6 weeks, the agency tested the eight substances in a number of high-throughput assays that probed a variety of biological pathways, including endocrine disruption animal testing articles for and against cytotoxicity, and produced a report identifying the toxicity profiles of the dispersants fortunately, the dispersant being most widely used at the time compared favorably to the others. If these studies had been conducted in animals, the testing and reporting would have taken years, and would likely have produced results no more conclusive than those obtained from the cell systems in a matter of weeks.

For the moment, regulators are reluctant to rely solely on tests based on cell and tissue systems, but as high-throughput systems data become better understood, the speed and cost advantages of these systems will inevitably drive researchers away from whole-animal studies. Current NIH director Francis Collins was an early animal testing articles for and against of modernizing toxicity testing, and is now seeking to do the same in efficacy testing.

Indeed, the movement away from animal testing articles for and against experimentation is already underway. Since the mid-seventies, the use of animals in experimentation read more fallen here around 50 percent.

Avoiding Animal Testing

animal testing articles for and against The number of animals held in laboratories of universities and research institutes declined dramatically until around the mids and then began to climb again as facilities began producing and maintaining genetically modified mouse strains.

However, data from Great Britain indicate that the actual use of mice by far the most-used laboratory species for research projects has plateaued in the last decade despite a large increase in the size of animal animal testing articles for and against articles for and against colonies. This overall go here in animal use can be attributed to the advent of novel technologies animal testing articles for and against as improved cell-culture systems and microanalytic techniques; more sophisticated model systems; improved understanding of signaling and metabolic pathways; and a host of other new methods that allow scientists to answer important animal testing articles for and against about the functioning of healthy animal testing articles for and against diseased tissues without subjecting whole animals to harmful procedures.

With a 50 percent decline in animal animal testing articles for and against sincewe are roughly at the halfway point towards the complete elimination of animal research.

Thus, we argue that, bywe might finally see the last of animal use writing great essay english the laboratory, particularly if all stakeholders put their minds to it.

Rowan, a Rhodes Scholar, has a doctorate in biochemistry.

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